ISSN 0964-5659

Longevity Report 44

Volume 6 no 44. First published April 1994. ISSN 0964-5659.

ESP Cooling Yvan Bozzonetti

Is Superstition an Illness Yvan Bozzonetti

Dead Man's Curve Bob Brakeman

Dental Products Douglas Skrecky

Letters: The last word on Haloperidol. The Fractals of Gods and Men.

Neurocryobiology Needs Papers

A Novel Treatment for Migraine Douglas Skrecky

The Origin of Life Douglas Skrecky

A Possible Cure for Rheumatoid Arthritis Douglas Skrecky

Taurine versus hepatitis B Douglas Skrecky

Who is Right? Chrissie Loveday

Aspirin News Yvan Bozzonetti

Some Ideas About Alzheimer's Disease Yvan Bozzonetti

Magnetic Therapy for Senile Dementia Douglas Skrecky

A Reply to Klaus Reinhard Douglas Skrecky



ESP Cooling.



by Yvan Bozzonetti



I must say I am somewhat cool about ESP. Mr. Brian W. Haines' paper in Longevity Report 43 left me with a mixed feeling. I think in a scientific domain we must always search for the simplest explanation and set to it. Water diviners make often a good living. In France they are most commonly used where geologists say there is a shallow water table. That is not to say the common water diviner is looking at geological maps, simply the practice survives where you could find some water by boring a shaft anywhere. What the specialist does is not water discovery but, he finds in a given area the best site to bore for the water at a shallower place.



To do that, he looks at traces of marsh-lowing vegetation, some flood or geological features such the lowest point in a field, or the basis of a cliff. If there is a river nearby, he knows any hole reaching the river level will get water. Because these rules are simple to follow, the business must be covered in the user's mind with some magical practice to justify the price for the advice.



There are also simple explanations about twin telepathy. True twins develop often some form of special language between them. This coded communication may include words without significance for any other, special tones of common words, gesture, signs and so on. The social pressures contribute greatly to the building of that form of underground communication. Very similar people living a similar life come often at a similar conclusion at the same time because they have the same background. For them and nearby observers, that may look as telepathy. When the process don't work, the psychological pressure is great to use the underground communication system to give a positive result at will. All of that is applied psychology in a particular social context, not extra sensory perception.



Well, this is my opinion and the simplest explanation but there will be always someone in need of miraculous facts, so the brain reading folks have some good days to live and so the people exploiting that credulity. Mr. Haines' twins example was inoffensive. That is not always the case with everybody.



The small incursion of unknown physics is not an explanation for brain reading and action at a distance. There are mathematical works on the subjects and the scientific material to build a theory about similar thing. This is the domain of noncontinuous spaces, a special branch of set theory. There are hard arguments to say brain reading cannot work, I think it is best to accept that statement, any further argument would become heavily loaded with incredibly long mathematical formulas.

Is Superstition An Illness?



by Yvan Bozzonetti



To ask this question is to say I think superstition is bunk.



That opinion comes from a personal experience:



One day, when I was doing a strenuous work, I was caught in a mental state where each thought, each action, seemed linked to another past action or idea. The result was very distressing and produced a high stress condition. Depending on your psychology, I assume there may be three ways to see such an effect:

First it can be perceived as a hell manifestation or some religious first hand product,

second as an ESP and

third as a product of bad digestion.

I settled for the last and recalled I was using both high doses of vitamin E derivative and aspirin (against a headache). That admixture, I realised, is very bad for the stomach and well adapted to produce a bad digestive problem with some depressive side effects.



Why that was it translating in so strong a bad mood feeling? I think it was linked to my high vitamin C intake. The explanation is quite simple ... on mathematical grounds. There is how I see things:



A brain is a very complex network including many loop-like pathways. This mesh structure is well known in mathematics to simulate a continuous space with differential properties. (This fact is exploited to simulate high energy experiments on programmed grids in large computer. The same process also works in weather forecast centres.) A brain is a limited domain, so the space it can simulate in a bounded one. Topology says any bounded orientable space is endowed with one left and one right oriented boundaries, each with one dimension less than the original space. Because brain processing takes place at the cell surfaces, such surfaces are indeed the oriented natural boundaries of a simulated space produced in three dimensions by the brain. There is too, says topology, a non-orientable boundary in an undefined space. In two dimensions, this is the so called projective plane, a mathematical object looking as a sphere surface where all points outside the equator are paired, with one element in each hemisphere. The equator is not an ordinary circle, but a Möebius strip.



I have said before how vitamin C induces a "divination state" with two scales of time. If they are associated with a simulated space on the brain, then any hard interruption must include a projective plane subspace state. I think the feeling was so strong because of the large dose of product used.



Daily life must produce similar effects of lesser amplitude, even if they get unnoticed individually, they must slowly drive the basic mental state to take into account irrelevant correlation between facts something very near superstition or religious faith.



I think it would be useful for many to know such effects are possible, even if you avoid any vitamin. Knowing that, I keep an "alarm bell" against any superstition derivative. and aspirin in GT-1 anti-oxidant.Dead Man's Curve



by Bob Brakeman



I was cruisin in my stingray late one night,

When an X K E pulled up on the right;

He rolled down the window of his shiny new Jag,

And challenged me then and there to a drag.



I said 'You re on Buddy', my mill's runnin' fine,

Let's come off the line now at Sunset & Vine;

But I'll go you one better if you've got the nerve,

Let's race all the way to Dead Man's Curve.



Dead Man's Curve is no place to play,

Dead Man's Curve -- you'd best keep away,

Dead Man's Curve -- I can hear 'em say:

Won't come back from Dead Man's Curve



The street was deserted late Friday night,

We were buggin each other while we sat out the light;

We both popped the clutch when the light turned green,

You shoudda heard the whine from my screamin' machine.



We flew past La Brea, Schwab's' and Crescent Heights,

And all the Jag could see were my six tail lights;

He passed me at Doheny and I started to swerve,

But I pulled her out & there we were -- at Dead Man's Curve

(Thunderous car - crash sounds)



Well, the last thing I remember, Doc, I started to swerve,

Then I saw the Jag slide into the Curve,

I know I'll never forget that horrible sight,

I guess I found out for myself everyone was right:



You won't come back from Dead Man's Curve ...1

This article is part of a trilogy2 of articles devoted to some informal survey research on the subject of what kinds of people make the most likely converts to immortalism.3 What we were interested in, this time around, was this question: If we could rank people on a continuum which reflects how big a disaster they think death is, would it be the case that those at the very-big-disaster end of the continuum would be more likely cryonics recruits than those at the no-big-deal end of the continuum?



To try to answer that question, we used this methodology: We hired college students to be storytellers. They cruised through neighbourhoods selected for certain demographic attributes4 and offered people a small sum of money for a few minutes of their time. That time was spent listening to our students tell them several little stories, all of them involving innocent deaths. They were then asked to rank their personal feelings about the conclusion to each story (with some innocent person getting annihilated) along the following continuum:

l "That's the worst thing I ever heard of".

2 "That's just terrible".

3 "That's extremely sad".

4 "That's pretty sad".

5 "That's a little bit sad".

6 "So what?"

While some of the individuals said that none of those exact words were the ones they would have used, we told them to choose the sentence which came closest to expressing their feelings and their intensity, irrespective of the precise wording.



Originally, our intention had been to play-the-folks-some-music. Instead of storytelling by college students, we were just going to have those students play the people certain rock and roll records from the Palaeozoic Rock period, beginning with the advent of Elvis in January 1956 and ending with the English Invasion in January of 1964. That P.R. period was famous for including as one of its subgenres what might be called Blood And Guts Rock --- rock songs in which the total number of deceased humans had increased by the end of the song. But we changed that original intention when the first few people who listened to the songs couldn't take the seriousness-of-death issue very seriously, when it was brought up in the context of a-buncha-rock-and-roll-records; the entertainment context wrecked the seriousness with which they were taking what they were being asked about. So we simply shifted gears and had the college students tell-the-stories involved in the rock hits, without using any of the names used in the songs or otherwise giving people clues that what they were hearing were the death-oriented plot lines of songs from the first R&R generation.



Those plots dealt with: Annihilation while driving on the city streets (Dead Man's Curve by Jan & Dean, the lyrics of which began this article); annihilation while having an encounter with a railroad train (Mark Dinning's Teen Angel, whose lyrics are in Appendix One); annihilation at a racetrack (Ray Peterson's Tell Laura I Love Her --- lyrics in Appendix One); and annihilation-by-drowning (Patches, by Dickie Lee; lyrics also in Appendix One). A second methodological change we had to make, in addition to shifting from playing records to storytelling, was that one record had to be dropped from the storytelling list --- The Last Person To See Me Alive, by Diana Trask. Although we badly wanted to include it (even its title was perfect for this kind of analysis), we had to drop it when the first several respondents uniformly said "He deserved it!" about the guy who gets killed. That lad differed from the other soon-to-be-dead-folks in the other songs by being a rotten character; since we were interested in assessing people's reactions to death mangling innocent people, we concluded that that song clouded the issue, so it was eliminated (with regret --- any song that contains a line like "Now the feeling he was feelin he ain't feelin anymore" right after the sound of a gun going off obviously has greatness in its pedigree).



After making the two adjustments described so far, we were still worried about one potential problem: We were afraid that if there were a lot of answers in the two middle-response categories (3-"That's extremely sad" & 4- "That's pretty sad") it too would cloud the issue, for it would harm our ability to say "OK, these are the people who take death seriously and these are the people who don't"; it would be harder to segregate them that way, in other words, if we were dealing with people whose responses were all quite close to each other in that 3/4 borderland. But we needn't have worried: There were almost no responses in that middle ground, and people fairly easily sorted themselves into two groups --- people with a strong tendency to see death as an incalculable diaster and those prone to see it 'as a natural part of things and all part of God's Great Plan. Once we had segregated people into the Good Guys and the Bad Guys, they were asked a second set of questions --- essentially the same ones asked the people interviewed for the other articles in this series: After they were given cryonics and other life- extension material to read, they were asked:

(A) Were you favourably or unfavourably impressed with the material you read?

(B) Would you consider reading a full-length book on the subject if we provided it?

(C) Would you consider joining a life-extension group?

(D) Do you consider the current 70-years-or-so lifespan "enough"?

(E) Would you consider donating money to a group which would do one or both of two things --- perform longevity research and/or cryonically suspend people?



On all five of those questions, there was a clear differentiation between those we labelled casual-about-death (people whose story-responses were, on average, in the little-bit-sad/who cares? part of the continuum) and those we labelled hostile-to-death (those whose responses on average were concentrated in the worst-thing/just-terrible part of the continuum). 71% of the hostile-to-death people (let's call them the HTD's) liked the immortalist literature they read, but only 38% of the casual-about-death people did (we'll call those folks the CAD's --- which pretty well sums up their character, come to think of it). 81% of the HTD's would read a book on cryonics but only 28% of the CAD's. 61% of the HTD's said they could see themselves joining a life-extension group, but only 19% of the CAD's. 74% of the HTD's thought 70-or-so was a rotten lifespan, but only 14% of the CAD's thought there was anything wrong with it. Finally, 59% of the HTD's said they could see themselves giving money to some life-extension cause, but only 8% (the only single-digit response) of the CAD's.



Two conclusions seem justified by these survey research results. The first is that while it's always dangerous to proceed on the basis on what everyone knows intuitively to be true --- in this instance what seemed logical going in turned out to be correct coming out: People who think of death as a grotesque and anti-moral imposition on human existence really are better potential recruits for cryonics than people who think "no problem we're just all going to sit at the feet of the baby Jesus."



Secondly, this little survey confirms once again the psychopathic nature of the assumption that all-us-humans-are-pretty-much alike: Huge numbers of people (the CAD's) simply can't think clearly about major issues, whether the issue is the annihilation-process or economic sanity or the government/criminal structure. It's a sad conclusion, but the Great Psycho Public simply isn't worth our time; spend your recruiting time on the minority of people who know that a syllogism isn't a new kind of silly putty. (But of course an exception must be made for people whose favourite sentence is "Well, the last thing I remember, Doc ..." & who've personally caressed Dead Man's Curve & who take off their hats reverently as they pass La Brea and Schwab's Drugstore and Crescent Heights while cruising Sunset Boulevard on their way to Malibu --- those people get frozen-free, no matter how dumb they are).



Notes:

1 Lyrics from Dead Man's Curve, recorded in late 1963 by the surfrock duo Jan and Dean on Liberty Records. Words and music by Jan Berry (of Jan and Dean), Brian Wilson (of the Beach Boys), Los Angeles pop writer Art Kornfeld, and Hollywood disc jockey Roger Christian. Dead Man's Curve, in addition to being a million-selling hit, is also a mini-guide to the Sunset Strip, going west on Sunset Boulevard beginning at Vine Street. It's also a "true" story, in certain respects: There really is a Dead Man's Curve, at a spot on Sunset where it suddenly makes a more-than-right-angle near Bel-Air. Lots of non-celebrities have been killed there, & a couple of celebs have come close --- both comedian Mel Blanc (the voice for Bugs Bunny & approximately every other cartoon character) & Ricky Nelson crashed cars there and barely lived. Also, Jan Berry, who wrote and produced and arranged and sang lead vocal on DMC, was nearly killed in his own Stingray while racing on a street a few miles from Sunset; his own personal version of DMC ended the career of Jan and Dean, as he suffered massive brain damage from which he is still recovering.

2 And can a tetralogy be far behind?

3 The other two articles are Who Needs Tahiti? and America Needs More Hostile Attitudes, both published in England's Longevity Report.

4 We wanted a mixture of rich/poor, black/white, urban/suburban, etc.



Appendix One:



In addition to Dead Man's Curve1 whose lyrics are given at the beginning of this article, these are the other songs whose stories were used in this project:



Patches,2 A million-seller by Dickie Lee3 in 1962. Words and music by Barry Mann and Larry Kolber:



Down by the river that flows by the coalyards,

Stand wooden houses with shutters torn down;

There lives a girl ev-rybody calls Patches,

Patches my darling of old Shanty Town.



We planned to marry when June brought the sun,

I couldn't wait to make Patches my bride;

Now I don't see how that ever can happen,

My folks say no and my heart breaks inside.



Patches, oh what can I do?

I swear I'll always love you.

But a girl from that place will only bring me disgrace,

So my folks won't let me love you.





Each night I cry as I think of that shanty,

And pretty Patches there watching the door;

She doesn't know that I can't come to see her,

Patches must think that I love her no more.



I hear a neighbour telling my father,

He says a girl name of Patches was found,

Floating face down in that dirty old river4

That flows by the coalyards in old Shanty Town.



Patches, oh what can I do?

I swear I'll always love you.

It may not be right but I'll join you tonight

Patches I'm coming to you."



Teen Angel, a million-seller by Mark Dinning in 1960. Words and music by Jean and Red Surrey:



That fateful night the car was stalled,

Upon the railroad track;

I pulled you out and we were safe,

But you went running back



What was it you were looking for

That took your life that night;

They say they found my high school ring,

Clutched in your fingers tight



Teen Angel, can you hear me?

Teen Angel, can you see me?

Are you somewhere up above,

And am I still your own true love?



Just sweet 16 & now you're gone

They've taken you away;

I'll never kiss your lips again,

They buried you today



Tell Laura I Love Her, a million-seller by Ray Peterson in 1960. Words and music by Jeff Barry and Ben Raleigh:



Laura and Tommy were lovers,

He wanted to give her everything;

Candy, presents, and most of all,

A wedding ring.



He saw a sign for a stock car race,

A thousand-dollar prize it read;

He couldn't get Laura on the phone,

So to her mother Tommy said:



Tell Laura I love her,

Tell Laura I need her;

Tell Laura I may be late,

I've something to do that cannot wait.



He drove his car to the racing ground,

He was the youngest driver there;

The crowd roared as they started the race,

'Round the track they drove at a deadly pace.



No one knows what happened that day,

How his car overturned in flames;

But as they pulled him from the twisted wreck,

With his dying breath they could hear him say:



Tell Laura I love her,

Tell Laura I need her;

Tell Laura not to cry,

My love for her will never die.



Now in the chapel where Laura prays,

For her Tommy who passed away,

It was just for Laura he lived and died,

Alone in the chapel she can hear him cry:



Tell Laura I love her,

Tell Laura I need her,

Tell Laura not to cry,

My love for her will never die.



Appendix Two:



These are the lyrics to the song whose story was dropped from the project, for\reasons explained in the text of this article:



The Last Person To See Me Alive, a hit by Diana Trask in 1971:



He was the very last person to see me,

The very last person to see me alive.

He packed up his old grey suitcase, threw his keys down on the bed,

Then he slowly started walkin' out the door,

And by way of explanation he just turned around & said,

That the feelin' he was feelin' he ain't feelin' anymore.



So I spent the empty evenings like a statue on the shelf,

And I spent the days just starin' at the wall;

And I knew I'd have to find him, or I'd never find myself,

Cuz livin' without lovin' ain't livin' after all.



He was the very last person to see me,

The very last person to see me alive.



Well I found him in a hotel , someone new was in his bed,

He just laughed as I came walkin' through the door;

So with the gun I bought to end my life I ended his instead,

Now the feelin' he was feelin' he ain't feelin' anymore.



And I was the very last person to see him,

The very last person to see him alive.



Notes to appendices:

1 The flipside of Dead Man's Curve was also a big hit (New Girl In School), but, sadly, no one died in it, so it was useless to us. When a TV-Movie was made of the life story of Jan Berry and Dean Torrance, it was inevitable that it would be called Dead Man's Curve. Jan Berry's career almost self-destructed at the beginning, just as his personal life came close to self destructing later: His first record was a very pure little item about a Hollywood stripper whose motto was "44 and Plenty More!". He called it Jennie Lee, The Bazoom Girl, which made his record company (owned by the purest of the semi-pure, Doris Day) refuse to release it; when he then renamed it just -Jennie Lee it was released, partly because the monster-echo was so intense that absolutely none of the lyrics was decipherable.

2 After the release of Patches, any girl with less-than-perfect clothing in high school was promptly given a new name.

3 Dickie Lee's voice was so sweet that people were always shocked when he showed up looking like he could take Dick The Bruiser two falls out of three.

4 Patches was such a huge hit that within the rock culture, every river in America was, thereafter, always referred to as "that dirty old river".

5 According to some charts, Teen Angel was the best selling record of the entire decade of the sixties --- and that in spite of the fact that about half the radio stations in the country wouldn't play it ("too morbid --- just the kind of anti-social trash we expect from rock and roll"). The song's astounding success began when Mark Dinning's sister, Jean Dinning Surrey (she'd been a member of the Dinning Sisters singing trio in the 4Os) read a magazine article in which someone was defending teens against the charge that rock and roll was turning them into juvenile delinquents; a quote from the article said that not all kids are teen devils --- "some of them are teen angels" Then Jean had a nightmare, & all she could remember of it was the line "They said they found my high school ring clutched in your fingers tight." She combined the two concepts and wrote Teen Angel with her husband Red. When she played it for her brother Mark at dinner, he put down his fork (who could eat during Teen Angel?) & picked up his guitar. When he recorded a sample tape & played it at a record store, within minutes people were coming in off the street & asking "What is that thing & can I buy it?"

6 The anguish in Ray Peterson's voice as he performed Tell Laura I Love Her & other songs was real: He was a polio patient & spent most of his time in an iron lung.



Good News Addendum:

When initiating this survey, we hoped that a certain side-benefit would materialize, and it has: Several of the people surveyed have become very interested in the life- extension technologies & are joining the couple of dozen people we've brought into the immortalist movement over the years.

Bob Brakeman, the author of more than 2000 articles on Immortalism and Public Affairs, resides in Las Vegas, Nevada.

Dental Products



by Douglas Skrecky



Toothpastes contain either sodium fluoride or sodium monofluorophosphate as anticaries agents. One could suppose these must be equally effective, since if they were not toothpaste manufacturers would have no choice but to use only the better of the two if they wished to remain competitive. Wrong. Tests have found sodium fluoride to be significantly more effective than sodium monofluorophosphate in preventing caries.1 Don't buy toothpastes containing sodium monofluorophosphate. Some toothpastes contain additional anticaries ingredients. Sanguinarine (Viadent) has little or no effect, but triclosan (Colgate Total) does inhibit the growth of plaque.2 Some toothpastes also contain potassium salts to treat dental hypersensitivity. Of these salts the most effective is potassium citrate.3



Not all mouthwashes are useful in inhibiting plaque. Plax for instance is reported to have no effect at all.4 Mouthwashes containing essential oils (Listerine) and quaternary ammonium compounds (Cepacol, Scope) do inhibit plaque.2



Chewing gum is not generally regarded as an essential part of dental hygiene, but nonetheless can be a very effective adjunct. Chewing gum which is sweetened with xylitol inhibits the growth of cavities, even 5 years after the regular use of this gum is stopped!5 Recently the Canadian Dental Association has recognized xylitol as an effective cavity fighting ingredient. This has greatly increased the sales of Trident sugarless gum, which contains the approved cavity fighter Dentec (a.k.a. xylitol).6



Since teeth contain a lot of calcium one would suppose that a high calcium diet could inhibit caries. Increased calcium content in plaque is associated with decreased caries.7 However not all calcium salts can increase plaque calcium. Calcium carbonate, calcium phosphate, calcium chloride and calcium gluconate do not inhibit caries development in rats when mixed with solid food. Calcium glycerophosphate is helpful when mixed with food, but has no effect when given in the drinking water.8 Calcium lactate inhibits caries in rats when either mixed with food or given in drinking water.9,10 In humans a calcium lactate mouthrinse has been documented to increase both calcium and phosphorus in plaque and to reduce calculus.11,12 Adding 7% calcium lactate to toothpaste also reduces calculus.13 The best time for administration of calcium lactate for maximal effectiveness is apparently after meals.14 Calcium lactate looks to be is a cheap, effective, non toxic cavity fighter. No commercially available toothpaste, no mouthwash and no chewing gum contains calcium lactate. Hopefully this will soon change. For now at least it is little trouble to add calcium lactate to mouthwashes.



1 A Critical Review of the Relative Anticaries Efficacy of Sodium Fluoride and Sodium Monofluorophosphate Dentifrices 337-360 Vol.27 1993 Caries Research

2 Agents for the Management of Plaque and Gingivitis 1450-1454 Vol.71 No.7 1992 Journal of Dental Research

3 Use of Multiple Sensitivity Measurements and Logit Statistical Analysis to Assess the Effectiveness of a Potassium Citrate Containing Dentifrice in Reducing Dentinal Hypersensitivity 256-261 Vol.19 1992 Journal of Clinical Periodontology

4 The Effect of Using a Pre-Brushing Mouthwash (Plax) on Oral Hygiene in Man 679-681 Vol.19 1992 Journal of Clinical Periodontology

5 Long Term Effect of Xylitol Chewing Gum in the Prevention of Dental Caries: A Follow-up 5 Years After Termination of a Prevention Program 495-498 Vol.27 1993 Caries Research

6 Gum Maker Smiling After Dentists Okay Trident Sugarless October 21,1993 The Globe and Mail

7 Plaque Minerals and Caries Experience: Associations and Interrelationships 427-432 Vol.57 No.3 1978 Journal of Dental Research

8 Protection Against Dental Caries in Rats by Glycerophosphates or Calcium Salts or Mixtures of Both 717-724 Vol.20 1975 Archives Oral Biology

9 Preliminary Studies on Calcium Lactate as an Anticaries Food Additive 12-17 Vol.16 1982 Caries Research

10 Effect of Calcium Lactate and Calcium Lactophosphate on Caries Activity in Programme Fed Rats 368-370 Vol.19 1985 Caries Research

11 Effect of a Mouthrinse Containing Calcium Lactate on the Formation and Mineralization of Dental Plaque 146-150 Vol.23 1989 Caries Research

12 Influence of Calcium Lactate Rinses on Calculus Formation in Adults 376-378 Vol.24 1990 Caries Research

13 Control of Calculus Formation by a Dentifrice Containing Calcium Lactate 277-279 Vol.27 1993 Caries Research

14 Effect of Timing of Administered Calcium Lactate on the Sucrose Induced Intraoral Demineralization of Bovine Enamel 187-191 Vol.37 No.3 1992 Archives Oral Biology

Editorial notes:

Mr Skrecky is reviewing various scientific papers that make statements about dental products. Longevity Report as a publication does not castigate or endorse particular products, and it is up to readers to follow the references and draw their own conclusions.

A further article on Dentistry will appear soon



Letters



From Mrs Joy Cass



I am truly thankful to say that since I prayed about my Haloperidol hang-up I have never had a moment's anxiety! Really, I haven't, and that was after 28 November, for on that night I took the two last tablets, for ever I hope! On Monday, 10 January I went to my general practitioner as I'd been plagued with mouth ulcers, and quite dreadful sneezing bouts, some lasting one to two hours. She prescribed a cream for the ulcers and a mouthwash, and was pleased I was off Haloperidol. (My GP had never put me on it, by the way - she realised my dislike of it.) In two days of cream and Oraldene the ulcers and sneezing cleared up. It is really wonderful how I have been released.



I am well aware of your words in Longevity Report 43, page 9 With regards to the Haloperidol, presumably you were prescribed it for mental agitation problems. Could not your God find some other way to help you with this? Are you aware of when agitation starts, and could you not say a Psalm to yourself or something to quell it? Excellent suggestion, just what was needed, and indeed what had been prayed for a week previously. Your acknowledgement of a healing God gave me support, encouragement and surprise!



So I was sad to read in your article A Longevist View of a Church Magazine (Longevity Report 43 page 17) To its credit as entertainment The Bible has a whole collection of rules ..., making a parody of "The Word", and rather snide fun of The Ten Commandments. I look upon these as a recipe for good and happy living. I think one has a better chance of serenity on oneself if one doesn't covet or kill or take the neighbour's spouse.



I must say that I always think it extraordinary when people ask why God allows human horror. My answer is that the creator gave mankind free will, so it is entirely mankind's responsibility if it insists on using this free will irresponsibly. Genesis chapter two verse 16: Freely eat. Verse 17: The taboo on the one tree, the tree of knowledge was more a warning of danger than a restriction of activity. Only one thing was refused out of the whole Garden of Eden. Chapter three verse 7-13 we find that no one will take responsibility Everyone's fault but mine they say.



But one can agree to differ, by not ridiculing others' opinions. But keep in mind the "no" we have to assert when evil intent is present. God makes it clear.



Comment



Thank you for your letter and for taking the trouble to comment on my article. I wonder how right it is to be sad at the idea of considering The Bible as entertainment.



Entertainment is fun, but it can also be informative and life enhancing. Years ago, at school, I have heard sermons saying that religion should also be fun.



Star Trek for example has made a big impression with its non-intervention rule. It may have influenced (rightly or wrongly) the allies' choice not to finish off Saddam Hussein after the Gulf War, but let Iraq determine its own destiny. People emulate heroes and villains in entertainment, which is why there is such a lot of debate about television violence. I do not feel that it belittles The Bible to regard it as entertainment, and neither do I feel that The Ten Commandments, whatever their merits, are different by any order of magnitude to any other rules for coexistence that have been devised. I certainly would agree that they make a good recipe for serene living. I think we corresponded in the past on another idea Do as you would be done by. Of course, The New Testament seeks change itself, replacing the ten commandments with only two.



I was pleased to hear that my suggestion with regards to agitation is still working, but unfortunately there are other explanations as to why it works than supernatural intervention. Your agitation comes from the mind, and it can be calmed chemically (with attendant unwanted side effects and possible damage to health) or by software. I could just as easily have recommended works of poetry or novels, but knowing your interest in The Bible felt that the Book of Psalms would be a suitable source of calming thoughts for you personally. Maybe I would have told an atheist who is a fan of The Hitchhiker Guide to the Galaxy to read from that or another Douglas Adams comedy. You should not credit me with religious belief, only logic (and a bit of good luck!).



Assuming truth is universal and outside personalities, it doesn't matter that much how one sees it. You describe things in terms of religion, I describe them in terms of science, reason or logic. For you it is easier to understand things in religious terms, for me in terms of logic. The problems arise when we start saying "I am right because I say so" or basing an argument on some quite unprovable proposition.



If Christianity is a religion powered by the direct word of God, then why isn't that word changing to take into consideration changing conditions? Why are there no more prophets, messiahs or messages blasted into stone? Or perhaps there would be a modern message, found written into a fractal or encoded into the digits of . Carl Sagan suggested the latter in his novel Contact. Maybe you would find it interesting to get this from the library and read it.



From Mr Dick Oliver



(This letter was addressed to Fractal Report, but I though it may interest Longevity Report readers more.)



The Fractals of Gods and Men



On the personal and trans-personal side, I certainly agree that many Christians (dare I say "most Christians"?) over the last couple millennia have had a tough time living up to the basic tenets of Christianity. Like you, I rather wince at the mention of Jesus, knowing his follower's abysmal track record. At the same time, however, I concur with what old J.C. was supposed to have taught and I do believe that striving consistently toward the purest, most holy part of one's self can have the happy side-effect of relieving one's weighty obsession with guilt. I also believe that consciousness is essentially a non-physical (that is, extra-sensory or non-sensory) phenomenon. Some folks call that sort of thing "spiritual" and I don't mind the terminology. By some methods of categorization, all those beliefs combined make me a Christian. I remain agnostic, however, about the spiritual origin of Jesus of Nazareth. Having not met the man, and not being clairvoyant enough to tell where he came from if I did, I prefer to worry about more current affairs.



One account of current affairs which I find particularly intriguing is Rudolf Steiner's predictions that the 21st century would see the human incarnation of one of two spiritual anti-christs. (Anti-christ number one, generally called Lucifer, supposedly incarnated 2000 years before Christ in the far East.) According to Steiner, an Austrian who died in 1923, and like-minded people, this second anti- christ, called Ahriman or Satan, is the master of intelligence and logic. Some say the computer and related technological devices are signs of Ahriman approaching our physical reality. I realize that all this probably sounds like drivel to you, and much of it does to me. But I find this account of history more true to my own perceptions of what's going on in the world than any other New Age blather I've come across. Incidentally, the desire for and promise of immortality is supposed to be one of Ahriman's calling cards, too. When Ahriman incarnates, his followers (which, so the story goes, are many) will be unusually intelligent and physically clear-sighted, but increasingly emotionally cold and heartless. I don't mean to suggest that you should take this "myth" seriously, but I found it intriguing and thought you might too.



I tell you all this only because I gather that you might enjoy hearing an honest perspective from someone you haven't met. I'd be interested to hear more about the beliefs which you classify as "anti-theist," if you have time and interest in writing about such lofty matters.



All my best to you for '94,



Comment:



As far as I am aware, the term antitheist was used by HG Wells in his book Mind at the End of Its Tether. But it is a long while ago I read it and I could be wrong.



To a certain extent we are all antitheists, as by using tools, wearing clothes, or living in houses we are imposing our wills over the natural (or God created) order of things. It is the "If God had meant us to fly he'd have given us wings" argument.



To be an immortalist (or even an emortalist) one is taking a stand against God's creation where we are (supposedly) designed to grow old and die.



The story in Genesis about the Garden of Eden and the knowledge of good and evil, and fig leaves, could in fact have psychological rather than historical significance. Suppose life in the garden represents life before birth, ie life in the womb, or even life as a small baby when mother provides everything. Suppose also that knowledge of good and evil represents not humanity's knowledge as a whole but that of each individual as it grows up.



Also, Genesis tells us that God made the entire universe and everything in it. This surely includes anti-Christs, such as Ahriman and other legendry aliens. As, by definition God is omnipotent, then these aliens are doing his will really. If anti-Christs appear on Earth and do a lot of damage of one sort or another, then they are only doing God's will.



The intriguing myths are more likely to be good subject matter for fictional films such as the Omen series than matter for serious debate as to the future of mankind.



"Neurocryobiology" Needs Papers



The January issue of Periastron, Dr Thomas Donaldson's newsletter of fact. hypothesis and speculation re cryonics and immortalism, contained more news about The Institute for Neural Cryobiology and its journal Neurocryobiology.



The journal has had only one article submitted for publication!



The purpose of this journal is to publish scientific works not allowed in cryobiological journals for political/racial/religious and other unscientific reasons.



The problem is, of course, that there is a world of difference between rattling off a column like this as opposed to preparing a fully referenced scientific paper. Indeed, I have come up with ideas in this column such as the cryostat using an expensive higher boiling temperature gas refluxed in using cheap liquid nitrogen. But to present this idea as a full worked paper, with experimental results and references, would be quite another matter. It would take some months of full time work to do properly, and requiring substantial expenditure on experimental equipment. If the person doing it was not fully conversant with cryogenic procedures, he would also have to take time learning them.



Maybe to get Neurocryobiology off the ground organisations with money available for research will have to order research projects from Russian laboratories and take advantage of the cheap professional labour and equipment left over from Communist scientific programmes. I understand from Venturist Monthly News and The Immortalist that there are large groups of immortalists working in Russia and they may well be able to help with such a project.



Unfortunately the only organisation I know of that was funding life extension research on a regular basis was the Life Extension Foundation of Florida, but its program was halted some years ago as a result of the need to pay lawyers in its ongoing battle with the FDA and other government bureaucrats.



Other topics covered in Periastron of January 1994 were Gott's conclusion on the Copernican Hypothesis, how neurons connect, tracing nerve connections to the heart, memory, nitric oxide and nerve growth, synapses, and rejoining severed nerves.



Periastron PO Box 2365, Sunnyvale, California 94087. Subscriptions cost $2.50 per issue. If you pay for many issues in advance, you avoid any possible price rises. If the newsletter does not continue for any reason, unused subscriptions will be refunded with interest!



A Novel Treatment

for Migraine



by Douglas Skrecky



Portable stroboscopes fashioned to look like sunglasses are being marketed as relaxation aids and are reputed to induce a Zen-like meditational state, without the years of preparation. Be that as it may, stroboscope glasses have been tested for their effects on migraine sufferers. The experimental glasses used a pair of red light emitting diodes to illuminate both eyes, while the eyelids were kept closed to diffuse the light. The brightness setting was user adjustable and the frequency could be varied from 0.5 to 50 Hz. Seven migraine patients were allowed to use these glasses as they saw fit to treat their condition. The results were dramatic. Of 50 migraines reported, 49 were helped by the glasses and 36 were stopped. The reported mean duration of migraine attacks without the use of the glasses was 6 hours and with the glasses this was reduced to 35 minutes. Average length of a session with the glasses was 30 minutes. The brightness control was used at its maximum setting as better results were obtained when the light source was brighter. Patients reported that relief was more rapid when the upper frequency range was used. The only side effects recorded were a feeling of calmness and relaxation.1,2

1 The Treatment of Migraine With Variable Frequency Photo-Stimulation 154-155 Vol.29 1989 Headache

2 Please note that epileptics and those suffering from photoconvulsive disorders such as pyrophobia should not be exposed to stroboscopes.



The Origin

of Life



by Douglas Skrecky



According to scientists it seems that life should never have arisen on earth. Life as we know it requires reduced nitrogen compounds. The problem with this requirement is that the atmosphere on earth is now known to never have been a reducing one, so reduced nitrogen compounds should never have formed. Yet here we are, so the trick must have been worked somehow. If it was pure dumb luck then life must be so rare that it exists only on one planet in the cosmos - Earth. Scientists don't believe in this kind of luck so the search for a plausible source of reduced nitrogen is on.



Recently one and only one plausible theory for this has come to light. At a pH between 7.3 and 9 and at temperatures above 25 C iron can reduce nitrates to ammonia, to provide the required reduced nitrogen source. However the amount of ammonia produced is still so little that the origin of life still rests on a very slim thread.1



1 Prebiotic Ammonia From Reduction of Nitrate By Iron II on the Early Earth 630-633 Vol.365 1993 Nature



A Possible Cure for

Rheumatoid Arthritis



by Douglas Skrecky



Rheumatoid arthritis is believed to originate from an autoimmune attack against joint cartilage. Oral administration of large amounts of foreign proteins are known to help induce tolerance to these proteins so an attempt was made to try to reduce autoimmune attack on joints by feeding 0.1 mg/day of solubilized type II collagen for the first month and then 0.5 mg/day for 2 additional months. All rheumatoid arthritis patients were taken off immunosuppresive drugs so as to allow tolerization to occur. No side effects were noted with this therapy and a decrease in the number of swollen joints in treated, but not control subjects occurred. Of the 60 treated patients, 4 achieved a complete remission of their disease.1 The next step in the further development of this promising therapy is to further increase the dosage of ingested collagen, try other materials and most importantly use immune boosting drugs such as coenzyme Q10 to see if a higher remission rate could be obtained.



1 Effects of Oral Administration of Type II Collagen on Rheumatoid Arthritis 1727-1730 Vol.261 1993 Science



Editorial note:

See also Life Extension Report 14,11, January 1994. The Life Extension Foundation have yet to locate a source of chicken cartilage, but plan to cover new treatments for rheumatoid arthritis in Life Extension Update over the next few months. Membership of the Life Extension Foundation is available for $69 ($50 USA residents) from PO Box 229120 Hollywood Florida 33022 USA. Benefits include discounts on vitamins and other products, two monthly newsletters, and new members get three free books: The Physicians' Guide to Life Extension Drugs, The Directory of Life Extension Doctors, and The Directory of Innovative Medical Clinics. Payment may be made by all major credit cards. If you have not used your credit card for overseas purchases before, you may be interested to know that you get the best possible exchange rate, as opposed to the extortionate charges made by other methods of getting foreign currency. If you just import books and magazines, there is no import duty or taxes to pay. The parcels are delivered to your door just like any ordinary post.



Taurine Versus Hepatitis B



by Douglas Skrecky



Hepatitis B vaccines are usually ineffective in stimulating an immune response against this virus. Oral supplementation with 12 grams of taurine on the day prior to as well as on the day of vaccination improves the odds of generating an anti-HB antibody response. After 12 months HB vaccine alone yielded a 28.6% response rate, while the combination HB vaccine/taurine increased this to 60.7%.1 One would also suppose that taurine would be of some use in the treatment of those already infected with hepatitis B, as well as other viral conditions.



1 A Novel Oral Adjuvant for Hepatitis B Virus (HBV) Vaccines 326-329 Vol.11 1990 Journal of Hepatology



Who is Right?



by Chrissie Loveday



It is a fact of life that people will make assumptions about each other. A long-haired, scruffy or leather clad man walking along the road, might be seen as a layabout, up to no good or threatening. Someone sitting in parked car may be assumed to be watching a place for some illegal purpose, casing the joint for possible burglary, perhaps? A woman wearing a wedding ring, is automatically assumed to be married, a man who does not wear one is not necessarily unmarried, but he could be. What we rarely take the time to see, is what that person is really like. Some of my closest friends have long hair and often look scruffy, but they are kind and loving and not a bit like the image they are projecting. A person in a wheelchair is not necessarily brainless or voiceless and it should be assumed they are unable to speak ... the "does he take sugar"? syndrome.

We must all, at some time, have looked at someone who is suffering and wondered what they have to live for? What possible motivation do they have to go on? Ask them, they will respond in various ways. The old lady crippled with arthritis can't wait for "her good Lord to take her". Some of us without her faith, would think she is tired of life and simply wants to end her pain. Euthanasia is not an option in Britain and so her life is prolonged. Others have a capacity for enjoying life for whatever it offers, just for the sake of living.



Working with profoundly disabled people, I often see them in a severe depression, often brought on by frustration at not being able to do anything for themselves. Those who do have good brains are often the worst, logically because they be aware of things they would like to be doing. Even the people who are most disabled can have some ambition, even if only to make their own choices about what they want to wear on a certain day. We cannot assume that what they "have to live for" is so little as to make it almost not worthwhile. There are times when to instil a little motivation becomes an uphill task and it is case of survival until a better day comes along. But to most of them, life is precious and they derive their own pleasures from living. Because we can't imagine how we would cope, does not mean that any life is not worth protecting.



As I get older, the things I want to do, seem to increase daily. Time goes faster and faster and I do not believe it just me, being less efficient. Some of my old friends may wonder what I find to do, buried in Cornwall, away from my previous busy life. Assumptions again! I seem to have found more to do than ever, with writing, my work at Cornwall College and so many beautiful things to see around me. However did I find time for those other activities and does it matter anyway, if some things don't get done? As long as I and anyone else concerned, are comfortable with it, life belongs to oneself to use in particular ways. Perhaps death, too.



My involvement with the cryonics movement is relatively recent. Talking about it to various people brings varied reactions. Inevitably, the "how much" comes into it and the well known responses are trotted out. For many people, there is the assumption it won't work and therefore those signed up are being conned, wasting money. Is it not equally wasteful to spend vast sums of money on maintaining buildings, churches, various investigative committees, law-suits, etc.? It is surely up to everyone to believe in what they are doing and if it does not hurt other people, why not have a few eccentrics around?



Those with deep religious beliefs suggest cryonics is quite wrong and potentially evil, but are they not making the assumption their beliefs are the right ones? Look at the vast range of ways of disposing of bodies, according to the different religions. Who is right? Those who incinerate? Those who bury in the ground, pointing in particular directions, vertically, upside-down, as in some traditions, curled up, in others? Is it really a total waste of money for those who burn huge symbolic piles of expensive paper, printed to look like money, cars, houses, videos etc., as in many Far Eastern countries? Because it is different, why should anyone ever dare to assume it is wrong?



The stress and grief brought by a death, expected or unexpected, can make decisions very difficult. Knowing the person's wishes, regarding funerals and disposal of the corpse is not always easy. It may be in direct conflict with you believe to be right, but surely wishes should be respected? Assuming the deceased was a little potty, not in proper control of their faculties, is no reason to do what you think is right and not what they wanted. If they were right all along, you would be guilty of denying them a chance. I will stick to what I think and believe and right or wrong, I hope others will respect my wishes.



Aspirin News.



by Yvan Bozzonetti



Aspirin is a pain killer, an anti-clotting agent and an anti-inflammatory product. Now, it seems each of these properties come from the action on a particular biochemical target, at least if I have understood two papers in the 20 January 1994 issue of Nature (NAT. 367 p;2215 and p. 243). That gives us the hope to see someday an aspirin-like product specific for each effect without side effects, for example bleeding associated with anti-inflammatory action. Because some senile dementia conditions seem associated with an inflammatory process, such an aspirin-like drug would be very interesting.



For present day action, the Nature articles give us at least one useful item: The anti-clotting property seems to rest on both the aspirin and cellular receptor concentrations. Under some given limit, the effect disappears. Clots are initiated in small vessels by platelet blood cells, a limited aspirin dose must block the relevant platelet receptors when they are concentrated in a narrow duct without action on similar receptors on stomach cells for example.



Because aspirin binding to the cell receptor site is irreversible, the activity remains during all the cell life, that is about ten days. A dose every five days would act on at least 3/4 of the circulating cells. The second paper give a suggested dosage near 75 mg, or less than 1/4 of a common 350 mg tablet. If that can prevent clotting and ensuing damages it is a cheap way to buy five more years or so of good life.



Some Ideas About Alzheimer's Disease



by Yvan Bozzonetti



When we have to fight against such a debilitating illness, any help seems welcome. Then why not to ask Longevity Report if there is not a (at least partial) solution? With such a help message in hand you try to find something, find nothing serious, and suggest some untested solution. Then come more and more help messages, whatever your first ideas you are now on the slippery slope turning you into a guru or something similar.



So I start with a note of caution: If I write about Alzheimer's Syndrome, my opinion is than we have no real solution. I am not a guru with a miracle cure and don't want to be taken for such. There is probably a genetic component in at least some Alzheimer-like syndromes. The solution is then beyond the reach of any amateur or single person.



If we can't act on the causative agent, may be there is a partial solution at the effects level? It seems a good part of the neuron destruction comes from a self defence reaction from the immune system, that is, an inflammatory reaction. An antibiotic with anti inflammatory properties exploited to fight the Lepra seems to give some results. This is a typical guru advice because I have no experience of it. If it work, the illness would be stopped in its evolution. To regain what has been lost is another story.



Looking at an even more cosmetic level, we can try to compensate temporally some brain damage effects. For example the 10th nerve starting from the central nervous system regulate both the heart pulse frequency and the function of smooth muscles in the digestive tract. Without it, the heart accelerates, digestion comes to near halt and sphincters remain open. Before looking at neurotransmitters, that is, the links between nerve cells, the first level to look may be the energy of the cells. Because the universal energy currency of cells is the adenosine triphosphate molecule (ATP), why not to try to boost its production? The inosine powder is a close precursor of ATP, so it would (could?) have some useful effects. (That product may be found in the Life + catalogue and, I assume, elsewhere).



There is an Alzheimer's case in my family and the above idea seems to work, at least for a short period. I have no long experience with it. Because there is no cure at the fundamental level, I guess we can only buy some time in this way. Piracetam, sold by Interlab, seems useful too as a general brain activity booster. In the long run it is liver toxic. Here too, more ATP in the liver can help that organ to cope with the toxicity side of the product. Inosine is then here a Piracetam complement.



Really, it is more comfortable to say: take this herb and there will be a miracle, have the faith, I am a guru. Sorry, I can't propose that, I have only a partial idea and a single limited result, something short of what is a true medical experiment.

Magnetic Therapy for Senile Dementia

by Douglas Skrecky



The application of weak magnetic fields to the pineal gland may constitute a major breakthrough in the treatment of senile dementia of various etiologies. The rationale for the treatment of Parkinson's disease is that melatonin inhibits the release of dopamine, while weak magnetic fields in turn inhibit the release of melatonin by the pineal gland.1 When magnetic therapy was finally tried on patients suffering from Parkinson's disease or multiple sclerosis even the researchers involved were surprised by the results.



Magnetic stimulation was applied to the patient's scalp by an array of 32 coils generating a field of 7.5 picoTesla at a frequency of 2-7 hertz for a period of 7 minutes, once per week. Placebo treated patients were unchanged but treated patients generally felt subjective relaxation within about 10 to 30 minutes after treatment. Blood pressure fell slightly and extremities felt cold. Parkinson's symptoms were improved with increased eye blink rate, steadier gait, improved speech, reduced hand tremor and improved handwriting. These improvements were maintained for 3 to 5 days after the first treatment, but were maintained for the full week after subsequent weekly treatments.2 Parkinson's patients who also suffered from Alzheimer's disease also experienced a considerable improvement in cognitive functioning.3 A patient suffering from multiple sclerosis experienced a rapid improvement, which could be reversed by administration of 3 mg of melatonin.4 Magnetic treatment of a second patient suffering from an acute relapse of multiple sclerosis produced a complete resolution of symptoms within two weeks after initiation of therapy.5



As magnetic therapy does not produce profits for the medical/drug establishment hierarchy the dramatic effects it apparently produces has been studiously ignored. This may soon change for reasons that have little to do with profit. Magnetic therapy has produced results that are currently beyond the reach of ANY drug therapy.6



1 Weak Magnetic Fields as a Novel Therapeutic Modality in Parkinson's Disease 1-15 Vol.66 1992 International Journal of Neuroscience

2 Weak Magnetic Fields in the Treatment of Parkinson's Disease With the 'ON-OFF' Phenomenon 97-106 Vol.66 1992 International Journal of Neuroscience

3 Magnetic Fields in the Therapy of Parkinsonism 209-235 Vol.66 1992 International Journal of Neuroscience

4 Successful Treatment of Multiple Sclerosis With Magnetic Fields 237-250 Vol.66 1992 International Journal of Neuroscience

5 Successful Treatment of an Acute Exacerbation of Multiple Sclerosis By External Magnetic Fields 97-105 Vol.70 1993 International Journal of Neuroscience

6 The author sent photocopies of some of above journal references to Dr. Morton Shuleman, who was responsible for the introduction of Deprenyl into Canada, but who's own Parkinson's disease is no longer responsive to this drug. Sadly the only reply consisted of a return of the references with one almost illegible word scrawled across the covering letter. That one word was "nonsense".



Editorial Comment.



Elsewhere, such as in Life Extension Report 12,11 November 1992, the benefits of melatonin consumption are given as extending lifespan, improving sleep patterns etc. It is not clear whether taking melatonin and Deprenyl and/or KH-3 at the same time is sensible or whether they are antagonistic. It could be that the dopamine release inhibition by melatonin is an unwanted side effect to its life enhancing benefits. If this is the case, then taking Deprenyl or KH-3 is almost mandatory if you wish to take melatonin as well. I have not found another article relating melatonin to dopamine release.



If the inhibition of dopamine release is an unwanted side effect of otherwise beneficial melatonin, then this gives credence to my hypothesis that the human body consists of a number of systems all of which produce unwanted side effects, and what we observe as ageing is the side effects winning out over the benefits of each system. If this conjecture is true, then taking vitamins and pharmaceuticals is not going to make a very great difference to the maximum lifespan, although it will provide some benefits in old age, such as the avoidance of surgery or incapacity. If we want to eliminate ageing altogether, then we will have to completely re-design the human body, and develop a way of making the new body as acceptable as the original, and transplant our programs and data (=soul) into it.



A Reply to Klaus Reinhard



by Douglas Skrecky



I would like to propose a possible solution to Klaus's concern regarding the delay between death and the beginning of suspension. Although reducing this delay with a pulse monitoring device which emits a loud noise if a pulse is not detected after a set period of time would indeed be helpful, by itself it may not be a complete solution to the problem of severe autolysis. Human corpses exhibit a vast range in the severity of autolytic changes over similar timeframes. For example significant autolysis of the pancreas from humans begins anywhere from less than 2 hours to over 40 hours postmortem.1 Most of the neurons in the brains of humans who expired from heart failure are destroyed within 3 hours of death, while control brains from dead animals show little deterioration.2



Thus it appears likely that even a pulse monitoring device is going to be inadequate to insure a high quality suspension in every case unless some means for insuring that the rate of autolysis is as low as possible is implemented before death.



Here's my suggestion for achieving this. All members of the cryonics movement could take a non-toxic one-a-day pill which would insure that when death does occur, that autolytic changes will occur slowly. The primary mechanism behind warm autolytic changes is known to be the calcium overload which occurs when the cellular membranes depolarize during anoxia. The highest rates of autolysis require disruption of cellular membranes so that extracellular calcium can enter cells quickly. This disruption is part of the free radical induced reperfusion injury which occurs when circulation is first interrupted and then temporarily restarted, as it is for instance during the final stages of heart failure. Supplemental vitamin E, riboflavin (vitamin B2), coenzyme Q10 and taurine are all known to reduce this injury when given singly. A supplement containing several of these substances should be particularly effective in inhibiting reperfusion induced membrane damage and thus insure that autolytic changes only occur slowly.



1 Postmortem Autolysis in the Pancreas: Multivariate Statistical Study 91-94 Vol.5 No.1 1990 Pancreas

2 Ultrastructural Changes of Neurons in Dependence on the Death Cause in Human Brain 231-234 Vol.2 No.4 1992 Functional and Developmental Morphology

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